End-to-End Custom Peptide Development
End-to-End Custom Peptide Development
Built on our proprietary AI protein large model as the core capability, we focus on peptide process-package delivery and full-chain capacity optimization. We provide a mature, production-ready process package spanning molecule optimization, synthetic process development, and pilot-scale validation. Uniquely, we also offer AI-driven optimization of tool enzymes for peptide production — using enzyme engineering to enhance the performance of key enzymes in the synthesis step.
Service Positioning
Our core capability is a self-developed AI protein foundation model. We focus on delivering peptide production process packages and full-process capacity optimization — providing both mature, production-ready process packages covering molecular optimization, synthesis process development, and pilot-scale validation, and our unique AI capability for optimizing tool enzymes used in peptide manufacturing. Through enzyme engineering, we enhance the performance of key enzymes in the synthesis stage, helping customers improve peptide synthesis yield, reduce production costs, and expand capacity along two dimensions: "process route optimization + core production enzyme optimization." The synthesis and production stages are executed in partnership with leading compliant peptide CDMOs, supporting full-process delivery from process development to commercial-scale manufacturing.
Data Tables
| Capability Dimension | Traditional Peptide CDMO | Our Service |
|---|---|---|
| Peptide Molecular Optimization | Mostly random mutation/sequence modification with high trial-and-error costs | AI large model rationally optimizes peptide sequences and modification schemes to improve activity, stability, and druggability; experimental workload reduced by 90% |
| Chemical Synthesis Process | Conventional process parameter optimization | AI-assisted optimization of fragment condensation strategies, coupling conditions, and purification routes to improve overall synthesis yield |
| Production Enzyme Optimization | Uses commercially available general-purpose enzymes with no customization capability | Proprietary capability: AI-directed engineering of key enzymes used in peptide production (proteases, ligases, modification enzymes, etc.) to improve enzyme activity, stability, and specificity, enhancing reaction efficiency and total capacity at the enzymatic catalysis stage |
| Deliverables | Only process parameters are delivered | A complete production-ready process package + customized and optimized production enzymes/strains; customers can directly proceed to mass production, with overall costs reduced by 20%–50% |
Service Process
Client Value
Yield improvement: Through dual-dimensional process and enzyme optimization, the overall yield of peptide synthesis is increased by 20%–50% compared with traditional processes.
Cost reduction: Through process optimization and reduced enzyme costs, the overall production cost of peptide APIs is lowered by 20%–40%.
Capacity improvement: After optimization of key enzyme performance, single-batch reaction time is shortened by 30%, and throughput per unit time is increased by over 40%.
Exclusive barriers: Customized, optimized production enzymes and supporting processes help clients build exclusive technical barriers in production.