Protein A Affinity Resin
Protein A Affinity Chromatography Resin This resin leverages specific binding interactions between its immobilized Protein A ligand and the Fc region of antibodies to achieve rapid capture and purification of target antibodies. Through targeted protein engineering of the Protein A ligand, the resin demonstrates high tolerance to 0.5–1.0 M sodium hydroxide (NaOH), which greatly extends its operational lifespan.
Product Details
This Protein A affinity chromatography resin enables rapid capture and purification of target antibodies via the specific binding interaction between its immobilized Protein A ligand and the Fc region of antibodies. The Protein A ligand has been protein-engineered for enhanced alkaline stability, enabling tolerance of 0.5–1.0 M NaOH, which greatly improves the resin's alkaline stability and significantly extends its operational lifespan.
This product is suitable for antibody purification from complex sample matrices such as cell culture supernatant, and supports use across all workflow stages: basic scientific research, process development, bench-scale validation, and large-scale commercial manufacturing. We provide customized support for product selection, process adaptation, and experimental validation, tailored to each customer's specific antibody type, sample conditions, and purification scale.
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Mild Elution Protein A Affinity Resin
Mild-Elution Protein A Affinity Chromatography Resin Developed via targeted engineering and optimization of the Protein A ligand, this resin elevates its elution pH to 5.0. It resolves the well-documented purification bottleneck for low-pH-sensitive antibodies, and is fully compatible with purification of complex bispecific antibody (bsAb) modalities.
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Protein L Affinity Resin
Protein L Affinity Chromatography Resin This resin enables rapid capture and purification of target antibodies via the highly specific binding interaction between its immobilized Protein L ligand and the kappa (κ) light chain of immunoglobulins.
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Protrin G Affinity Resin
Protein G Affinity Chromatography Resin Native Protein G is a bacterial cell surface protein originally isolated from Lancefield groups C and G Streptococcus species. It binds immunoglobulin G (IgG) via highly specific recognition of the antibody Fc region, and is widely used for antibody purification workflows. Compared to Protein A, Protein G exhibits broader species cross-reactivity and superior coverage of diverse IgG subclasses.
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